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"Health is not a commodity that can be bought, sold or traded. It is your own responsibility!"

Anthony Mossop

Colorectal Cancer

Information Regarding Colorectal Cancer

Colorectal Cancer Cancer of the large bowel is rare in the pediatric age group: 1 person per 1 million younger than 20 years in the United States annually.

These tumors can occur anywhere in the colon or rectum and are often associated with a family cancer syndrome. There is an increasing risk of colorectal cancer in members of families with a family history of intestinal polyps, which can lead to the development of multiple adenomatous polyps benign tumors. Juvenile polyps are not associated with an increased incidence or risk of cancer.

Colorectal cancer usually presents with symptoms related to the site of the tumor. Changes in bowel habits are associated with tumors of the rectum or lower colon. Tumors of the right colon may cause more subtle symptoms but are often associated with an abdominal mass, weight loss, decreased appetite, and blood in the stool. Any tumor that causes complete obstruction of the large bowel can cause bowel perforation and spread of the tumor cells within the abdominal cavity.

Colorectal carcinoma is rarely diagnosed in a pediatric patient however, vague gastrointestinal symptoms should alert the physician to investigate this possibility. Most patients present with evidence of metastatic disease cancer that has spread to other body parts, either as gross tumor or as microscopic deposits in lymph nodes, on the surface of the bowel, or other organs within the abdomen.

Complete surgical removal should be the primary aim of the surgeon, but in most instances, this is impossible removal of large portions of tumor provides little benefit for the individuals with extensive metastatic disease.

Most patients with microscopic metastatic disease generally develop gross metastatic disease, and few individuals with metastatic disease at diagnosis become long-term survivors. Current therapy includes the use of radiation therapy for rectal and lower colon tumors, in conjunction with chemotherapy.

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