"A certificate of qualification is simply a stepping stone to further knowledge."

Diana Mossop

Muckle-wells syndrome

Definition

First described in 1962 by Thomas James Muckle and Michael Vernon Wells, Muckle-Wells syndrome is also known as Urticaria-deafness-amyloidosis (UDA). It is a rare autosomal disease, which causes sensorineural deafness, recurrent hives, and can lead to amyloidosis. MWS happens when a mutation in the CIAS1 gene leads to increased activity of the cryopyrin protein. The disorder is closely related to two other syndromes, familial cold urticaria and neonatal onset multisystem inflammatory disease.

Diagnosis

Diagnostic criteria are purely clinical but genetic diagnosis is considered currently feasible. There are only moderate non-specific signs of inflammation during the course of inflammatory attacks associated to the disorder. Biochemical analyses may be useful to exclude certain diseases that can be considered as a function of the clinical signs present.

Symptoms and Signs

The common symptom for MWS is inflammation all over the body, which includes, fever, arthritis, and malaise. The chronic inflammation associated with MWS can lead to deafness. Prolonged inflammation can also lead to deposition of proteins in the kidney, a condition known as amyloidosis.

Causes

The disease is caused by a defect in the CIAS1 gene, which creates the protein cryopyrin.

Testimonials

We have a growing number of testimonials from patients who want to spread the word about Phytobiophysics.

We have recently returned from annual leave and T???'s face looks so much thinner. A friend that has not seen her for a fortnight remarked on what a large change she has seen in her. She said that she thought she used to look like…

Some 16 months ago following a long period of ill health and frequent visits to doctors, In desperation I visited Diana. I was at the time suffering from a progressively debilitating shoulder pain and a re-occurrence of chroni…

I am a practitioner of Phytobiophysics based in Malaysia. When I first started practicing Phybiophysics, my friend's 6 months old baby suffered with leukemia. I have used Phytobiophysics flower formulas to help him and together wi…

I attended the Institute of Phytobiophysics for a consultation for a general check up. My practitioner advised me that she thought that I was suffering with a condyloma condition which would result in genital warts. I was surp…

I trained in anatomy and physiology, then on to aromatherapy and then went through reiki on to masters through the years and still felt I needed some more strings to my how to help others. So I went on to do Kinesiology foundation…

I feel blessed to have been introduced to these amazing formulas. I have been seeing Val Finlayson for many years and with her knowledge and with the use of the phytos have overcome ME. I had my first baby boy three and a half ye…

blog comments powered by Disqus
It is believed by many professionals worldwide that the colours of the rainbow have a direct relationship to the human body and health.