"My Mission is to bring affordable, ethical and effective healthcare, using the natural healing power of plants, to the children of the world, not just my children but all children, in my life time."
First described in 1962 by Thomas James Muckle and Michael Vernon Wells, Muckle-Wells syndrome is also known as Urticaria-deafness-amyloidosis (UDA). It is a rare autosomal disease, which causes sensorineural deafness, recurrent hives, and can lead to amyloidosis. MWS happens when a mutation in the CIAS1 gene leads to increased activity of the cryopyrin protein. The disorder is closely related to two other syndromes, familial cold urticaria and neonatal onset multisystem inflammatory disease.
Diagnostic criteria are purely clinical but genetic diagnosis is considered currently feasible. There are only moderate non-specific signs of inflammation during the course of inflammatory attacks associated to the disorder. Biochemical analyses may be useful to exclude certain diseases that can be considered as a function of the clinical signs present.
The common symptom for MWS is inflammation all over the body, which includes, fever, arthritis, and malaise. The chronic inflammation associated with MWS can lead to deafness. Prolonged inflammation can also lead to deposition of proteins in the kidney, a condition known as amyloidosis.
The disease is caused by a defect in the CIAS1 gene, which creates the protein cryopyrin.
Patient UK information on Muckle-wells syndrome.
We have a growing number of testimonials from patients who want to spread the word about Phytobiophysics.
As you are aware, my son, who is six years old, was a perfectly normal baby, until he had his MMR vaccine. After this, he was slightly unwell, I then noticed almost immediately that he had no eye contact with me or anyone else, an…
I would like to thank you for all the help that you have given me over the last 18 months. Although I was aware of how much you have helped other members of my family for various ailments, I confess that I remained sceptical — to …
My son who is 3yrs old has recently been suffering from persistent attack of Impetigo. It first appeared on his mouth which after taking a seven day course of antibiotics cleared up and disappeared, but unfortunately within a fort…
Having suffered from skin problems all my life, and having a doctor in the family, I am well placed to comment on the short-comings of traditional medicine in treating conditions like mine.
After years of dragging vainly betwee…
I am writing to thank you for your treatment of me and my family.
I first came to you in early March this year, when I had been recently diagnosed as a Diabetic. I was shocked and upset about this diagnosis, fearful of the futu…
When I visited you a month ago I was suffering from serious Oedema, my ankles were very swollen – I take Lisinopril for my heart and my doctor prescribed water tablets.
Unfortunately they made me feel so ill I did not wont to t…
Phytobiophysics® Formulas are a food supplement and do not claim to diagnose, treat or cure medical conditions.
The information provided on this website is the personal opinion of Diana Mossop and/or Anthony Mossop unless otherwise stated.
All data and information provided on this site is for informational purposes only. DianaMossop.com makes no representations as to accuracy, completeness, currentness, suitability, or validity of any information on this site and will not be liable for any errors, omissions, or delays in this information or any losses, injuries, or damages arising from its display or use. All information is provided on an as-is basis.