"Health is not a commodity that can be bought, sold or traded. It is your own responsibility!"
First described in 1962 by Thomas James Muckle and Michael Vernon Wells, Muckle-Wells syndrome is also known as Urticaria-deafness-amyloidosis (UDA). It is a rare autosomal disease, which causes sensorineural deafness, recurrent hives, and can lead to amyloidosis. MWS happens when a mutation in the CIAS1 gene leads to increased activity of the cryopyrin protein. The disorder is closely related to two other syndromes, familial cold urticaria and neonatal onset multisystem inflammatory disease.
Diagnostic criteria are purely clinical but genetic diagnosis is considered currently feasible. There are only moderate non-specific signs of inflammation during the course of inflammatory attacks associated to the disorder. Biochemical analyses may be useful to exclude certain diseases that can be considered as a function of the clinical signs present.
The common symptom for MWS is inflammation all over the body, which includes, fever, arthritis, and malaise. The chronic inflammation associated with MWS can lead to deafness. Prolonged inflammation can also lead to deposition of proteins in the kidney, a condition known as amyloidosis.
The disease is caused by a defect in the CIAS1 gene, which creates the protein cryopyrin.
Patient UK information on Muckle-wells syndrome.
We have a growing number of testimonials from patients who want to spread the word about Phytobiophysics.
I would like to give a testimonial about my grandson for your web site I seem to be unable to upload recommendations myself.
'My six year old grandson is growing up in a world where the use of synthetic oestrog…
I went to see my GP in February 1998 after experiencing pins and needles in my left arm and fingers. At first I thought it may have been just a trapped nerve but after it continued for a week and I began to feel worse in myself no…
I trained in anatomy and physiology, then on to aromatherapy and then went through reiki on to masters through the years and still felt I needed some more strings to my how to help others. So I went on to do Kinesiology foundation…
I am writing to thank you for your treatment of me and my family.
I first came to you in early March this year, when I had been recently diagnosed as a Diabetic. I was shocked and upset about this diagnosis, fearful of the futu…
Dear Diana I really thank you for the little blue pills that you have prescribed for me. I want to tell everyone how important the Pharma Nord Prelox is. On the silver box it says ‘a patented male sexual pleasure enhancer’ and t…
Huge thanks to you Diana for all you have done for me and my son! We came to you in despair as all the doctors said that they could not help nor diagnose the problems he had, (recurrent nausea, jaw pain and anxiety) and we were a…
Phytobiophysics® Formulas are a food supplement and do not claim to diagnose, treat or cure medical conditions.
The information provided on this website is the personal opinion of Diana Mossop and/or Anthony Mossop unless otherwise stated.
All data and information provided on this site is for informational purposes only. DianaMossop.com makes no representations as to accuracy, completeness, currentness, suitability, or validity of any information on this site and will not be liable for any errors, omissions, or delays in this information or any losses, injuries, or damages arising from its display or use. All information is provided on an as-is basis.