"Natural medicine is really all about common sense."
First described in 1962 by Thomas James Muckle and Michael Vernon Wells, Muckle-Wells syndrome is also known as Urticaria-deafness-amyloidosis (UDA). It is a rare autosomal disease, which causes sensorineural deafness, recurrent hives, and can lead to amyloidosis. MWS happens when a mutation in the CIAS1 gene leads to increased activity of the cryopyrin protein. The disorder is closely related to two other syndromes, familial cold urticaria and neonatal onset multisystem inflammatory disease.
Diagnostic criteria are purely clinical but genetic diagnosis is considered currently feasible. There are only moderate non-specific signs of inflammation during the course of inflammatory attacks associated to the disorder. Biochemical analyses may be useful to exclude certain diseases that can be considered as a function of the clinical signs present.
The common symptom for MWS is inflammation all over the body, which includes, fever, arthritis, and malaise. The chronic inflammation associated with MWS can lead to deafness. Prolonged inflammation can also lead to deposition of proteins in the kidney, a condition known as amyloidosis.
The disease is caused by a defect in the CIAS1 gene, which creates the protein cryopyrin.
Patient UK information on Muckle-wells syndrome.
We have a growing number of testimonials from patients who want to spread the word about Phytobiophysics.
How we can ever thank you for all the help you have given us in “finders” our “lost” little boy today 3½ . Through your flower formulas he has improved so much that people now think we are wrong when we say that he is Autistic. He…
I writing this letter firstly as a THANK YOU and secondly to tell you how you have changed my life and the life of my baby daughter M???.
When M??? was born she seemed to cry all the time and the Hospital and my doctor put this…
My name is Paul Clements and I won the individual and team gold medals in the IX Nat West Island Games Triathlon, held on 8th July 2001.
Prior to the games I was suffering with a tight chest and feeling generally fatigued. Havi…
I went to see my GP in February 1998 after experiencing pins and needles in my left arm and fingers. At first I thought it may have been just a trapped nerve but after it continued for a week and I began to feel worse in myself no…
Having suffered from skin problems all my life, and having a doctor in the family, I am well placed to comment on the short-comings of traditional medicine in treating conditions like mine.
After years of dragging vainly betwee…
I am writing to thank you for your treatment of me and my family.
I first came to you in early March this year, when I had been recently diagnosed as a Diabetic. I was shocked and upset about this diagnosis, fearful of the futu…
Phytobiophysics® Formulas are a food supplement and do not claim to diagnose, treat or cure medical conditions.
The information provided on this website is the personal opinion of Diana Mossop and/or Anthony Mossop unless otherwise stated.
All data and information provided on this site is for informational purposes only. DianaMossop.com makes no representations as to accuracy, completeness, currentness, suitability, or validity of any information on this site and will not be liable for any errors, omissions, or delays in this information or any losses, injuries, or damages arising from its display or use. All information is provided on an as-is basis.