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Moersch-Woltmann syndrome, also known as stiff person disease, is a rare neurological disorder that causes severe muscle stiffness which could lead to paralysis.
The disease is diagnosed by conducting hemoglobin A1C tests to detect diabetes, as well as thyroid-stimulating hormone test to search for thyroiditis. It can also be diagnosed by looking for anti-GAD antibodies.
The symptoms of the disease include muscle stiffness in the limbs and lower trunk, back curves, stiff-legged walk, muscle spasms and extreme weakness.
The Moersch-Woltmann syndrome is an autoimmune disease; it can be caused by other disorders such as thyroiditis and type 1 diabetes.
Patient UK information on Moersch Woltmann Syndrome.
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